15.13 - Summary15.13 - Summary
In this lesson, among other things, we learned:
- Distinguish between situations where a crossover design would or would not be advantageous.
- Use the following terms appropriately: first-order carryover, sequence, period, washout, aliased effect.
- State why an adequate washout period is essential between periods of a crossover study in terms of aliased effects.
- Evaluate a crossover design as to its uniformity and balance and state the implications of these characteristics.
- Understand and modify SAS programs for analysis of data from 2x2 crossover trials with continuous or binary data.
- Provide an approach to analysis of event time data from a crossover study.
- Distinguish between population bioequivalence, average bioequivalence and individual bioequivalence.
- Relate the different types of bioequivalence to prescribability and switchability