8.10 - Summary

In this lesson, among other things, we learned:

  • Identify three benefits of randomization
  • Distinguish simple randomization from constrained randomization.
  • State the purpose of randomization in permuted blocks.
  • State the objective of stratified randomization.
  • Contrast the benefits of permuted blocks to those of adaptive randomization schemes.
  • Use a SAS program to produce a permuted blocks randomization plan.
  • Use an allocation ratio that will maximize statistical power in the situation where greater variability is expected in one treatment group than the other.
  • Provide the rationale against randomizing prior to informed consent.