Example 94 Section
Up until now, we have used the critical region approach in conducting our hypothesis tests. Now, let's take a look at an example in which we use what is called the Pvalue approach.
Among patients with lung cancer, usually, 90% or more die within three years. As a result of new forms of treatment, it is felt that this rate has been reduced. In a recent study of n = 150 lung cancer patients, y = 128 died within three years. Is there sufficient evidence at the \(\alpha = 0.05\) level, say, to conclude that the death rate due to lung cancer has been reduced?
Answer
The sample proportion is:
\(\hat{p}=\dfrac{128}{150}=0.853\)
The null and alternative hypotheses are:
\(H_0 \colon p = 0.90\) and \(H_A \colon p < 0.90\)
The test statistic is, therefore:
\(Z=\dfrac{\hat{p}p_0}{\sqrt{\dfrac{p_0(1p_0)}{n}}}=\dfrac{0.8530.90}{\sqrt{\dfrac{0.90(0.10)}{150}}}=1.92\)
And, the rejection region is:
Since the test statistic Z = −1.92 < −1.645, we reject the null hypothesis. There is sufficient evidence at the \(\alpha = 0.05\) level to conclude that the rate has been reduced.
Example 94 (continued) Section
What if we set the significance level \(\alpha\) = P(Type I Error) to 0.01? Is there still sufficient evidence to conclude that the death rate due to lung cancer has been reduced?
Answer
In this case, with \(\alpha = 0.01\), the rejection region is Z ≤ −2.33. That is, we reject if the test statistic falls in the rejection region defined by Z ≤ −2.33:
Because the test statistic Z = −1.92 > −2.33, we do not reject the null hypothesis. There is insufficient evidence at the \(\alpha = 0.01\) level to conclude that the rate has been reduced.
Example 94 (continued) Section
In the first part of this example, we rejected the null hypothesis when \(\alpha = 0.05\). And, in the second part of this example, we failed to reject the null hypothesis when \(\alpha = 0.01\). There must be some level of \(\alpha\), then, in which we cross the threshold from rejecting to not rejecting the null hypothesis. What is the smallest \(\alpha \text{ level}\) that would still cause us to reject the null hypothesis?
Answer
We would, of course, reject any time the critical value was smaller than our test statistic −1.92:
That is, we would reject if the critical value were −1.645, −1.83, and −1.92. But, we wouldn't reject if the critical value were −1.93. The \(\alpha \text{ level}\) associated with the test statistic −1.92 is called the Pvalue. It is the smallest \(\alpha \text{ level}\) that would lead to rejection. In this case, the Pvalue is:
P(Z < −1.92) = 0.0274
So far, all of the examples we've considered have involved a onetailed hypothesis test in which the alternative hypothesis involved either a less than (<) or a greater than (>) sign. What happens if we weren't sure of the direction in which the proportion could deviate from the hypothesized null value? That is, what if the alternative hypothesis involved a notequal sign (≠)? Let's take a look at an example.
Example 94 (continued) Section
What if we wanted to perform a "twotailed" test? That is, what if we wanted to test:
\(H_0 \colon p = 0.90\) versus \(H_A \colon p \ne 0.90\)
at the \(\alpha = 0.05\) level?
Answer
Let's first consider the critical value approach. If we allow for the possibility that the sample proportion could either prove to be too large or too small, then we need to specify a threshold value, that is, a critical value, in each tail of the distribution. In this case, we divide the "significance level" \(\alpha\) by 2 to get \(\alpha/2\):
That is, our rejection rule is that we should reject the null hypothesis \(H_0 \text{ if } Z ≥ 1.96\) or we should reject the null hypothesis \(H_0 \text{ if } Z ≤ −1.96\). Alternatively, we can write that we should reject the null hypothesis \(H_0 \text{ if } Z ≥ 1.96\). Because our test statistic is −1.92, we just barely fail to reject the null hypothesis, because 1.92 < 1.96. In this case, we would say that there is insufficient evidence at the \(\alpha = 0.05\) level to conclude that the sample proportion differs significantly from 0.90.
Now for the Pvalue approach. Again, needing to allow for the possibility that the sample proportion is either too large or too small, we multiply the Pvalue we obtain for the onetailed test by 2:
That is, the Pvalue is:
\(P=P(Z\geq 1.92)=P(Z>1.92 \text{ or } Z<1.92)=2 \times 0.0274=0.055\)
Because the Pvalue 0.055 is (just barely) greater than the significance level \(\alpha = 0.05\), we barely fail to reject the null hypothesis. Again, we would say that there is insufficient evidence at the \(\alpha = 0.05\) level to conclude that the sample proportion differs significantly from 0.90.
Let's close this example by formalizing the definition of a Pvalue, as well as summarizing the Pvalue approach to conducting a hypothesis test.
 PValue

The Pvalue is the smallest significance level \(\alpha\) that leads us to reject the null hypothesis.
Alternatively (and the way I prefer to think of Pvalues), the Pvalue is the probability that we'd observe a more extreme statistic than we did if the null hypothesis were true.
If the Pvalue is small, that is, if \(P ≤ \alpha\), then we reject the null hypothesis \(H_0\).
Note! Section
By the way, to test \(H_0 \colon p = p_0\), some statisticians will use the test statistic:
\(Z=\dfrac{\hat{p}p_0}{\sqrt{\dfrac{\hat{p}(1\hat{p})}{n}}}\)
rather than the one we've been using:
\(Z=\dfrac{\hat{p}p_0}{\sqrt{\dfrac{p_0(1p_0)}{n}}}\)
One advantage of doing so is that the interpretation of the confidence interval — does it contain \(p_0\)? — is always consistent with the hypothesis test decision, as illustrated here:
Answer
For the sake of ease, let:
\(se(\hat{p})=\sqrt{\dfrac{\hat{p}(1\hat{p})}{n}}\)
Twotailed test. In this case, the critical region approach tells us to reject the null hypothesis \(H_0 \colon p = p_0\) against the alternative hypothesis \(H_A \colon p \ne p_0\):
if \(Z=\dfrac{\hat{p}p_0}{se(\hat{p})} \geq z_{\alpha/2}\) or if \(Z=\dfrac{\hat{p}p_0}{se(\hat{p})} \leq z_{\alpha/2}\)
which is equivalent to rejecting the null hypothesis:
if \(\hat{p}p_0 \geq z_{\alpha/2}se(\hat{p})\) or if \(\hat{p}p_0 \leq z_{\alpha/2}se(\hat{p})\)
which is equivalent to rejecting the null hypothesis:
if \(p_0 \geq \hat{p}+z_{\alpha/2}se(\hat{p})\) or if \(p_0 \leq \hat{p}z_{\alpha/2}se(\hat{p})\)
That's the same as saying that we should reject the null hypothesis \(H_0 \text{ if } p_0\) is not in the \(\left(1\alpha\right)100\%\) confidence interval!
Lefttailed test. In this case, the critical region approach tells us to reject the null hypothesis \(H_0 \colon p = p_0\) against the alternative hypothesis \(H_A \colon p < p_0\):
if \(Z=\dfrac{\hat{p}p_0}{se(\hat{p})} \leq z_{\alpha}\)
which is equivalent to rejecting the null hypothesis:
if \(\hat{p}p_0 \leq z_{\alpha}se(\hat{p})\)
which is equivalent to rejecting the null hypothesis:
if \(p_0 \geq \hat{p}+z_{\alpha}se(\hat{p})\)
That's the same as saying that we should reject the null hypothesis \(H_0 \text{ if } p_0\) is not in the upper \(\left(1\alpha\right)100\%\) confidence interval:
\((0,\hat{p}+z_{\alpha}se(\hat{p}))\)